ANRS Trial number 12 206
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International phase 2b randomized clinical trial to assess two once-daily simplified antiretroviral triple therapies among HIV infected children treated early by a twice daily triple therapy between 6 and 52 weeks of age and in virological success in Africa
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The main objective is to compare the virological efficiency (proportion of success = follow up of
virologic failure) a once daily dose of two simplified triple therapies (monodose) that could allow
the protease inhibitors (ABC-3TC-EFV) or not (ABC-3TC-LPV/r), in a phase 2b-3 randomised controlled-trial
among HIV-infected children above the age of 15 months old and in virologic success after a 12 months
initial phase with a twice daily triple therapy using AZT-3TC-LPV/r.
The expected results for this study, will allow to :
Trial is done in Ivory Coast and in Burkina Faso.
Clinical trial registered or www.clinicaltrials.gov: NCT01127204